I'm a Syracuse alum, and I voted for Wade. He has had some incredible games, and I really don't think anyone has played as consistently well as he has over the first four games. Collison had one monster game (against Duke), and is a vital part to the success of Kansas, but he has disappeared at times (much like Carmelo Anthony). Wade has been the central driving force behine Marquette the whole tournament.
Collison's probably had the best single performance against Duke, but Wade's consistent greatness in both the Pitt and Kentucky games makes him my choice.